Centella asiatica: phytochemistry and mechanisms of neuroprotection and cognitive enhancement

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Current Updates on Centella asiatica: Phytochemistry, Pharmacology and Traditional Uses

Plants have been demonstrated extraordinary source of medicine, and recently focus on medicinal plant research has increased. Centella asiatica is well known for its traditional uses and medicinal properties for the treatment of many diseases. The published literatures mention the use of this plant as whole and bioactive compounds isolated are widely used in the treatment of various human ailme...

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Centella asiatica in cosmetology

Centella asiatica known as Gotu Kola is a medicinal plant that has been used in folk medicine for hundreds of years as well as in scientifically oriented medicine. The active compounds include pentacyclic triterpenes, mainly asiaticoside, madecassoside, asiatic and madecassic acids. Centella asiatica is effective in improving treatment of small wounds, hypertrophic wounds as well as burns, psor...

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Triterpene composition and bioactivities of Centella asiatica.

Leaves of Centella asiatica (Centella) were analysed for their triterpene composition and bioactivity such as collagen enhancement, antioxidant, anticellulite and UV protection capacity properties. Triterpenes of Centella were measured using HPLC-PAD on an Excil ODS 5 mm (C18) column for the simultaneous determination of asiatic acid, madecassic acid, asiaticoside and madecassoside. Centella wa...

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Antinociceptive and antiinflammatory effects of Centella asiatica

Objective: To evaluate the effects of Centella asiatica (CA) upon pain (antinociception) and inflammation in rodent models. Material and Methods: The antinociceptive activity of the water extract of CA (10, 30, 100 and 300 mg/kg) was studied using acetic acid-induced writhing and hot-plate method in mice. The antiinflammatory activity of CA was studied in rats by prostaglandin E 2 -induced paw ...

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Clinical and therapeutic benefits of Centella asiatica

Centella asiatica belongs to family Apiaceae is a traditionally important plant with wide range of therapeutic potential. Plant is traditionally used to treat a broad range of diseases such as diarrhea, hepatitis, measles, toothache, syphilis, leucorrhoea etc. Madecassic acid, asiatic acid, α-terpinene, α-copaene, β-caryophyllene are some of the important bioactive compounds responsible for its...

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ژورنال

عنوان ژورنال: Phytochemistry Reviews

سال: 2017

ISSN: 1568-7767,1572-980X

DOI: 10.1007/s11101-017-9528-y